Inhibition of Naegleria fowleri by microbial iron-chelating agents: ecological implications
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چکیده
منابع مشابه
Inhibition of Naegleria fowleri by microbial iron-chelating agents: ecological implications.
Deferrioxamine B and rhodotorulic acid, iron-chelating agents of microbial origin, exerted a pronounced inhibitory effect on pathogenic Naegleria fowleri at microgram levels. This inhibition was diminished by adding iron to the chelators before incubation with Naegleria isolates. These and related microbial iron chelators occur naturally in the environment. This could be of considerable ecologi...
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Naegleria fowleri causes acute and fulminant primary amoebic meningoencephalitis. This microorganism invades its host by penetrating the olfactory mucosa and then traveling up the mesaxonal spaces and crossing the cribriform plate; finally, the trophozoites invade the olfactory bulbs. During its invasion, the protozoan obtains nutrients such as proteins, lipids, carbohydrates, and cationic ions...
متن کاملNaegleria fowleri meningoencephalitis.
A 7-year-old boy with no prior illness or altered immunity presented to the emergency department with a 36-hour history of fever (103.7°F), emesis, headache, and lethargy. The patient had a history of swimming in a local lake the week before presentation. Physical examination revealed nuchal rigidity. Computed tomography (CT) of the head was normal. A lumbar puncture revealed a cerebrospinal fl...
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ABBREVIATIONS B103: Brain cell line 103, CDC: Centers for Disease Control and Prevention, CHO: Chinese Hamster Ovary, CMI: Cell mediated immunity, CNS: Central nervous system, CSF: Cerebro-spinal fluid, E6:Vero monkey kidney cell culture, HLF: Human lung fibroblast, HMG: High mobility group protein, HSP70: Heat shock protein 70, IFA: Immunoflurescent assay, ITS: Internal transcribed spacers, kD...
متن کاملFatal primary meningoencephalitis caused by Naegleria fowleri.
Naegleria fowleri is a free living parasite which habitats in fresh water reservoirs. It causes a fatal nervous system infection known as primary amoebic meningoencephalitis by invading through cribriform plate of nose and gaining entry into brain. We report a case of primary amoebic meningoencephalitis caused by Naegleria fowleri in Karachi, Pakistan, in a 42 years old male poultry farm worker...
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ژورنال
عنوان ژورنال: Applied and Environmental Microbiology
سال: 1983
ISSN: 0099-2240,1098-5336
DOI: 10.1128/aem.45.2.665-668.1983